Praeruptorin A ( —— )

产品货号. M19050 CAS No. 73069-27-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Praeruptorin A
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Praeruptorin A 通过靶向钙调蛋白并抑制 Ca(2+)/钙调蛋白-CaMKIV-CREB-NFATc1 和/或 Ca(2+)/钙调蛋白-钙调磷酸酶，具有抑制体外破骨细胞迁移/融合和体内骨侵蚀的潜力-NFATc1信号轴。
产品描述

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
体外实验

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体内实验

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同义词

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通路

GPCR/G Protein
靶点

Antibacterial
受体

CAM
研究领域

Others-Field
适应症

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1. Xu Z1, Wang X, Dai Y, Kong L, et al..Chem Biol Interact. 2010 Jul 30;186(2):239-46.

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